Because the ITB & Infinite Bark Builder have been built using the Sapling addon and the nodes that come shipped with Blender, it should work in any version of Blender that has these nodes, though I would always recommend anything above 2.8 to be certain as this is the version it was built in. All of the Infinite Builders are fairly GPU intensive, on an RTX 2060 with 8gb ram and 16gb system memory, it's very smooth in the viewport, but on a mac with a 12-year old ATI HD5770, the updates are somewhat slower, but still workable.

The only limitation you will find is how many subdivisions your system can handle and render for the Displacement Effects. It was built on an i7 8th Gen 8750H, an NVIDIA RTX 2060 with 16Gb ram.